Modern in vitro fertilization (IVF) protocols used worldwide generally involve ovarian stimulation with high doses of hormonal medications. The main goal of such stimulation is to obtain multiple mature eggs in a single menstrual cycle, which increases the chances of successful fertilization and pregnancy.

Although hormonal stimulation is generally well tolerated and rarely causes serious complications, it does place a significant burden on a woman’s body. This is especially important in cases where several IVF attempts are required. Moreover, in some cases, hormonal stimulation may be medically contraindicated.

At Vitromed Clinic, IVF can be performed without the use of hormonal stimulation — in the natural menstrual cycle. This approach is known under various names: “natural cycle”, “mild stimulation” or “minimal stimulation” but the essence remains the same — retrieving a single egg that has matured naturally.

During this procedure, the doctor monitors ovulation and retrieves the mature egg, which is then fertilized in the laboratory.

The benefits of this method include:

• Minimal interference with the woman’s hormonal balance;
• No risks associated with ovarian hyperstimulation;
• More comfortable physical and emotional well-being for the patient.

However, it is important to note that the success rate of IVF in a natural cycle is statistically lower than that of standard protocols: the likelihood of pregnancy is about 10–15% (compared to 30–40% with conventional IVF). This is due to several factors: not every mature egg can be retrieved, not all of them are fertilized, and there is no opportunity to select among multiple embryos — as is possible with the classic procedure.

Nevertheless, IVF in a natural cycle is an important and valuable alternative for women for whom hormonal stimulation is contraindicated or for those who prefer a gentler approach. At our clinic, you can receive a full consultation and choose the optimal infertility treatment method — with maximum attention to your health and individual needs.